A case of thymoma mimicking an intra-thoracic thyroid nodule

Auteurs-es

  • Cristina Pizzimenti Department of Biomedical, Dental, Morphological and Functional Imaging Sciences Department of Human Pathology in Adult and Developmental Age “Gaetano Barresi” University of Messina
  • Giovanni Tuccari Department of Biomedical, Dental, Morphological and Functional Imaging Sciences Department of Human Pathology in Adult and Developmental Age “Gaetano Barresi” University of Messina
  • Antonio Ieni Department of Biomedical, Dental, Morphological and Functional Imaging Sciences Department of Human Pathology in Adult and Developmental Age “Gaetano Barresi” University of Messina
  • Francesca Mazzeo Department of Biomedical, Dental, Morphological and Functional Imaging Sciences Department of Human Pathology in Adult and Developmental Age “Gaetano Barresi” University of Messina
  • Gianlorenzo Dionigi Department of Biomedical, Dental, Morphological and Functional Imaging Sciences Department of Human Pathology in Adult and Developmental Age “Gaetano Barresi” University of Messina
  • Guido Fadda Department of Biomedical, Dental, Morphological and Functional Imaging Sciences Department of Human Pathology in Adult and Developmental Age “Gaetano Barresi” University of Messina

DOI :

https://doi.org/10.13129/1828-6550/APMB.109.2.2021.CCS2

Mots-clés :

thymoma, mediastinal masses, ectopic thyroid goiter, differential diagnosis

Résumé

Thymomas are rare malignant tumour of the superior and anterior mediastinum. We report the case of a 77-year-old woman with a mediastinal nodule of uncertain origin. The clinical history of the patient and the imaging findings were suggestive of a lesion of thyroid origin. Histological and immunohistochemical analysis led to a histological diagnosis of thymoma with microscopic invasion of the surrounding tissue

Références

1. Markowiak, T., Hofmann, H.S., Ried M. (2020). Classification and staging of thymoma. J Thorac Dis, 12(12):7607–12. doi: 10.21037/jtd-2019-thym-01

2. Engels, E.A. (2010). Epidemiology of thymoma and associated malignancies. J Thorac Oncol, 5 (10 Suppl 4):S260-5. doi: 10.1097/JTO.0b013e3181f1f62d.

3. Scorsetti, M., Leo, F., Trama, A., D'Angelillo, R., Serpico, D., Macerelli, M., Zucali, P., Gatta, G., Garassino, M.C. (2016). Thymoma and thymic carcinomas. Crit Rev Oncol Hematol, 99:332-50. doi: 10.1016/j.critrevonc.2016.01.012

4. Duwe, B.V., Sterman, D.H., Musani, A.I. (2005) Tumors of the mediastinum. Chest, 128(4):2893-909. doi: 10.1378/chest.128.4.2893.

5. Patel, K.M., Parsons, C.C. (2016) Forgotten goiter: Diagnosis and management. A case report and literature review. Int J Surg Case Rep, 27:192-194. doi: 10.1016/j.ijscr.2016.08.036.

6. Juanpere, S., Cañete, N., Ortuño, P., Martínez, S., Sanchez, G., Bernado, L. (2013) A diagnostic approach to the mediastinal masses. Insights Imaging, 4(1):29-52. doi: 10.1007/s13244-012-0201-0.

7. den Bakker, M.A., Roden, A.C., Marx, A., Marino, M. (2014). Histologic classification of thymoma: a practical guide for routine cases. J Thorac Oncol, 9(9 Suppl 2):S125-30. doi: 10.1097/JTO.0000000000000297.

8. Marx, A., Chan, J.K., Coindre, J.M., Detterbeck, F., Girard, N., Harris, N.L., Jaffe, E.S., Kurrer, M.O., Marom, E.M., Moreira, A.L., Mukai, K., Orazi, A., Ströbel, P. (2015) The 2015 World Health Organization Classification of Tumors of the Thymus: Continuity and Changes. J Thorac Oncol, 10(10):1383-95. doi: 10.1097/JTO.0000000000000654.

9. Detterbeck, F.C., Nicholson, A.G., Kondo, K., Van Schil, P., Moran, C. (2011) The Masaoka-Koga stage classification for thymic malignancies: clarification and definition of terms. J Thorac Oncol, 6(7 Suppl 3):S1710-6. doi: 10.1097/JTO.0b013e31821e8cff.

Ried, M., Eicher, M.M., Neu, R., Sziklavari, Z., Hofmann, H.S. (2017). Evaluation of the new TNM-staging system for thymic malignancies: impact on indication and survival. World J Surg Oncol. 2017 Dec 2;15(1):214. doi: 10.1186/s12957-017-1283-4.

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Publié

2020-08-26

Numéro

Vol. 109 No. 2 (2021)

Rubrique

CLINICAL CASE SEMINAR

Licence

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