Dysphagia as initial manifestation of Guillan-Barrè Syndrome in a child
DOI :
https://doi.org/10.6092/1828-6550/APMB.105.1.2017.A7Mots-clés :
dysphagia, Guillain-Barrè syndrome, flaccid paralysisRésumé
The occurrence of dysphagia in a child may be a sign of various pathological conditions and mainly gastrointestinal disorders; neurological causes are not very frequent, but they should be taken in to considerations. Etiological diagnosis is important for minimizing related complications. Here we report the case of a 6-year-old girl who was admitted to our Clinic with sudden onset weakness of the limbs and dysphagia. Physical examination revealed hypo-areflexia of both legs and arms and multiple cranial nerve dysfunction. Based on typical clinical course, laboratory investigations and electrophysiological studies, a diagnosis of Guillain-Barrè Syndrome (GBS) was assessed. A treatment with intravenous immunoglobulin (IVIG) was immediately started with a progressive recovery of motility and cranial nerve function.
An electrophysiological evaluation, performed one month after therapy start, showed slight improvement of neurological symptoms, in particular of the sensitive component. On the basis of our experience we suggest that a GBS should be suspected when dysphagia is associated with pain and ascending flaccid paralysis of the limbs, in order to prevent a severe complications such as respiratory failure.
Références
Neocleous C, Diakolios K, Adramerina A , Varveris E, Tsioni V , Machairidou K. (2015) Guillain-Barré Syndrome presenting as unilateral hip pain in a child. Acta Medica Academica; 44(2):191-97.
Ryan MM. (2005) Guillain-Barré syndrome in childhood. J Paediatr Child Health;41:237-41.
Gunatilake SS, Gamlath R, Wimalaratna H. (2016) An unusual case of recurrent Guillain-Barré syndrome with normal cerebrospinal fluid protein levels: a case report. BMC Neurology,16:161.
Seneviratne U. (2000 Dec) Guillain-Barré Syndrome. Postgrad Med J. ;76(902):774-82.
Kuitwaard K, van Koningsveld R, Ruts L, Jacobs BC, van Doom PA. (2009) Recurrent Guillain–Barré Syndrome. J Neurol Neurosurg Psychiatry;80:56–9.
Wakerley BR, Yuki N. (2013) Infectious and noninfectious triggers in Guillain-Barré syndrome. Expert Rev Clin Immunol;9:627–39.
Wakerley BR, Yuki N. (2015 Apr) Mimics and chameleons in Guillain–Barré and Miller Fisher syndromes. Pract Neurolhttps://www.ncbi.nlm.nih.gov/pubmed/25239628">.;15(2):90-9.
Karimzadeh P, Bakhshandeh Bali MK, Nasehi MM, Taheri Ttaghsara SM, Ghofrani M. (2012 Autumn) Atypical Findings of Guillain-Barré Syndrome in Children. Iran J Child Neurol. 6(4): 17–22.
Ogna A, Prigent H, Lejaille M, Samb P, Sharshar T, Annane D, Lofaso F, Orlikowski D. (2017 Feb) Swallowing and swallowing-breathing interaction as predictors of intubation in Guillain-Barré syndrome. Brain Behav.; 7(2): e00611
Téléchargements
Publié
Numéro
Rubrique
Licence

This work is licensed under a Creative Commons Attribution 4.0 International License.
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).