Sporadic Micromedullary Thyroid Carcinoma and Hashimoto’s Thyroiditis: a case report and review of the literature

Autores/as

  • Giuseppe Turiano Endocrine Unit; Department of Medicine, Papardo Hospital Messina, Messina<strong> </strong>

DOI:

https://doi.org/10.6092/1828-6550/APMB.106.2.2018.A9

Palabras clave:

Thyroid Carcinoma, Medullary Thyroid Carcinoma, Hashimoto’s Thyroiditis, Calcitonin

Resumen

The incidence of Thyroid Cancer (TC) is increasing worldwide during the last decades. A link between TC and inflammation is well documented. A frequent association between Papillary Thyroid Carcinoma (PTC) and Hashimoto’s Thyroiditis (HT) is known, but  the coexistence of HT and Medullary Thyroid Carcinoma (MTC) is rare. We present a rare case of HT and Medullary Thyroid microCarcinoma (microMTC

Referencias

1. Russ, G., Bonnema, S., Erdogan, M.F., Durante, C., Ngu, R. and Leenhardt, L. (2017) European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS. Eur Thyroid J, (6): 225-237.

2. Mian, C., et al. (2014) Refining Calcium Test for the Diagnosis of Medullary Thyroid Cancer: Cutoffs, Procedures, and Safety. J Clin Endocrinol Metab, 99: 1656–1664

3. Resende de Paiva, C., Gronoi, C., Feld-Rasmussen, U. and von Buchwald, C (2017) Association between Hashimoto’s Thyroiditis and Thyroid Cancer in 64,628 Patients. frontiers in Oncology, 7:53

4. Zayed, A.A., et al. (2015) Is Hashimoto’s thyroiditis a risk factor for medullary thyroid carcinoma? Our experience and a literature review. Endocrine, 48 (2): 629–636.

5. Kazaure, H.S., Roman, S.A., Sosa, J.S. (2012) Medullary Thyroid Microcarcinoma A Population-Level Analysis of 310 Patients. Cancer, February 1: 620-627.

6. Machens, A. and Dralle, E. (2012) Biological Relevance of Medullary Thyroid Microcarcinoma. J Clin Endocrinol Metab, 97(5): 1547-1553.

7. Saltiki, K., Rentziou, G., Stamatelopoulos, K., Georgiopoulos, G., Stavrianos, C., Lambrinoudaki, E., Alevizaki,M. (2014) Small medullary thyroid carcinoma: post-operative calcitonin rather than tumour size predicts disease persistence and progression. European Journal of Endocrinology, 171: (1) 117-126.

8. Wells, A., et al. (2015) Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma. The American Thyroid Association Guidelines Task Force on Medullary Thyroid Carcinoma. THYROID Number 6 DOI: 10.1089/thy.2014.0335

9. Costante, G., Meringolo, D., Durante, C., Bianchi, D., Nocera, M., Tumino, S., Crocetti, S., Attard, M., Maranghi, M., Torlontano, M., Filetti,S. (2007) Predictive Value of Serum Calcitonin Levels for Preoperative Diagnosis of Medullary Thyroid Carcinoma in a Cohort of 5817 Consecutive Patients with Thyroid Nodules. J Clin Endocrinol Metab, 92: 450-455.
10. Colombo, C., Verga, U., Mian, C., Ferrero, S., Perrino,M.,Vicentini, L., Dazzi, D., Opocher,G., Pelizzo, M.R., Beck-Peccoz,P. and Laura Fugazzola (2012) Comparison of Calcium and Pentagastrin Tests for the Diagnosis and Follow-Up of Medullary Thyroid Cancer. J Clin Endocrinol Metab, 97(3): 905–913

11. Pelizzo, M.R., Torresan, F., Boschin, I.M., et al. (2013) Early, prophylactic thyroidectomy in hereditary medullary thyroid carcinoma: a 26-year mono institutional experience [published online ahead of print October 4,]. Am J ClinOncol. doi:10.1097/COC.0b013e3182a78fec.

Romei, C., et al. (2012) Low Prevalence of the Somatic M918T RET Mutation in Micro-Medullary Thyroid Cancer. Thyroid, 22 (5) doi.org/10.1089/thy.2011.0358

Descargas

Publicado

2018-12-18

Número

Sección

CLINICAL CASE SEMINAR